Clinical trial of ayurvedic remedy for COVID-19 shows groundbreaking results

A groundbreaking interim report on a clinical trial being conducted in three hospitals has shown that COVID-19 patients on natural treatment, based on the Indian traditional systems of herb-based medicines, are resolving most symptoms earlier than those on conventional medicines. The interim report on combination treatment of an ayurvedic remedy called 'Immunofree' by Corival Life Sciences, and Nutraceutical called 'Reginmune' by Biogetica have shown exceptional results as against the present government SOP of conventional medicines for coronavirus treatment.

Numerous tests such as C reactive protein, Procalcitonin, D Dimer and RT-PCR for novel coronavirus are also showing 20 to 60 per cent better improvement for the natural treatment, when compared to conventional treatment.

Numerous subjective endpoints such as body pain and fatigue are also leaning towards the natural treatment. Both Clinician's Global Assessment of Symptoms and Subject's Global Assessment of Symptoms clearly showed improvements on both arms showing more significant data in the test group.

About 86.66 per cent of patients on the natural protocol have tested corona negative on day 5 vs 60 per cent of patients on the conventional treatments. Moreover, on the 10th day test, all patients were negative, which could help in keeping the hospitals less occupied.

Immunofree and Reginmune are being studied in a one-of-a-kind pharmaceutical controlled multicentre clinical trial in 3 hospitals, in India. This CTRI-approved trial is being conducted on moderate COVID-19 positive patients at Government Medical Hospital, Srikakulam Andhra Pradesh, Parul Sevashram Hospital, Vadodara, Gujarat, and Lokmanya Hospital Pune, Maharashtra.

What sets this trial apart is the fact that it is the only time where half the patients in the trial have been given only natural treatment, which is being compared against the conventional treatment in use in India for COVID-19 patients.

This comparative study was achieved as a pilot study in Mumbai showed similar startling results. This control on the randomised trial allows for a direct comparison between these protocols from the world of natural medicine and conventional medicine.

The conventional treatment in use depends on the severity of the patient and includes HCQ, Azithromycin, Favipiravir and Cetirizine. This trial also has a broader inclusion criteria than others conducted on natural medicine as it includes patients upto 70 years old, with low oxygen saturation and co-morbidities.

It is significant to note that none of the patients on the natural treatment progressed past moderate, needed ventilators or had any adverse events. These precedent setting results have led to accelerated enrolment into this trial and statistically significant results should be ready by month end.

Numerous countries and states that have adopted or mandated natural treatment for novel coronavirus have shown mortality rates less than 1/10 of their neighbours. China supposedly stopped the outbreak after mandating TCM treatment.

Goa and Kerala both have 1/10th the mortality rate of neighbouring states. Madagascar, Central African Republic, Ghana and other countries which adopted COVID Organics have seen tremendous results compared to other African countries that did not adopt the natural treatment. WHO has now endorsed a clinical trial protocol for COVID natural medicines and this is one of the first studies proving natural medicine for COVID.

It is therefore hoped that India too mandates the use of these herbs for novel coronavirus treatment. All these regions tend to be using a subset combination of Glycyrrhiza Glabra, Artemisia, Hypericum Mysorense, Tinnispora Cardiflora, Inula Racemosa, Andrographis Paniculata and others contained in Immunofree which has 15 ingredients.

"Most remedies in use for COVID-19 are repurposed anti-malaria and anti-viral drugs not made specifically for this new virus that presents itself in ways no virus ever has. We are fortunate to have gotten approval for a very specific remedy that is now showing these startling results beyond our own expectations. It is a matter of great pride for India that our ancient sciences are coming to the forefront with this new empirical evidence and showing the importance of Ayurveda in the pandemic," Biogetica founder Apurve Mehra said.

"The results of this study thus far are startling and I hope to see people across the globe helped by this multifaceted natural remedy, which seems to apply to all who are pre-Covid, Covid positive and post-Covid. We are now approaching AYUSH and ICMR to get listed as the first herbal treatment of Covid in India, and look forward to government support in seeing this helping Indians and India," Wockhardt Foundation founder Huzaifa Khorakiwala said. (IANS) Source: r

Read More........→October 04, 2020

Wondering if you really need that dental treatment? Here’s what to ask and how to get a second opinion

Chanae Ihimaera, Auckland University of Technology

If the dental bill has ever made you gulp, you’re far from alone. Around three in ten Australian adults say they avoid or delay dental care due to costs. In Aotearoa New Zealand, almost half of adults overall have unmet dental needs due to cost.

Dental pain or symptoms of infection can be clear signs you might need a dental restoration such as a filling. But like tyres on a car or paint on a house, fillings and crowns wear over time and will eventually need to be replaced.

Let’s look at how long dental restorations usually last, what to ask your oral health practitioner if they’ve recommended these treatments, and how to get a second opinion if you’re still unsure.

How long are fillings, crowns and implants supposed to last?

How long they last depends on the material, how big the repair is, your oral habits, and even how well you care for your mouth at home.

Composite fillings are the most common type used today. They are made from a strong mix of resin and fine glass particles and are designed to blend in with your teeth and bond closely to the layers of teeth (enamel and dentine). Composites typically last 5–15 years. Their lifespan depends on your risk of dental decay, the force of your bite and the size of the cavity. Fillings most often fail when there is new decay or cracks in the surrounding tooth structure.

Crowns are used when a tooth needs more support than a filling can provide, for example after a root canal or when a tooth has large cracks. Most crowns last 10–15 years. Many last longer with regular check-ups and careful home care.

Dental implants are often described as the closest thing to a natural tooth replacement and with good care, can last decades. But they are not a “fit and forget” solution. Implants require long follow-up, not just the first year or two. This should include routine professional cleaning, checks for gum inflammation and monitoring that the implant and screws stay secure.

So your oral health practitioner has recommended treatment? What to ask

If your oral health practitioner recommends treatment, especially if it’s expensive or invasive, consider asking the following questions to get a better sense of your options:

• can you explain what the problem is in plain language?
• what are my options, including the least invasive?
• what happens if I wait or choose not to treat this right now?
• are there lower-cost options that would still work well?
• are there habits or risk factors that could shorten this option’s lifespan?
• can you give me a written treatment plan with itemised fees?
• is there anything else I should know before deciding?

Your oral health practitioner should talk through what the treatment involves, why they’re recommending it, the alternatives (including choosing to do nothing), likely outcomes, costs and give you space to ask questions.

Treatment shouldn’t go ahead until you understand everything and feel comfortable agreeing.

If you want to explore your options, seek a second opinion. This is not a sign of distrust – it’s good self-advocacy and ensures your treatment choices align with your values, budget and long-term wellbeing.

So how do you get a second opinion? What might change?

Getting a second opinion can be simple as booking in with a second oral health practitioner and let them know you’re seeking their advice. You can ask your usual clinic to email your notes or X-rays if you want to take them to a second provider.

A second opinion means asking another oral health practitioner for their view on your diagnosis or recommended treatment. People usually seek a second opinion when:

• the issue is complex
• the treatment is major or expensive
• they want to explore less invasive or more cost-effective options
• they want to clarify before committing.

This advice can make it easier to decide what course of action aligns with your values, such as whether you favour low intervention or would rather avoid the risks of delaying treatment.

While the evidence is limited in oral health, a study of medical care found 37% of patients received a different treatment recommendation when they sought a second opinion.

Second opinions in medicine often lead to meaningful changes in diagnosis or treatment. Individual studies found changes in as few as 10% or as many as 62% of second opinion cases.

Most patients across the study and review reported high satisfaction with the process.

What are your rights as a patient?

Under Aotearoa New Zealand’s Privacy Act and the Code of Health and Disability Services Consumers’ Rights, you’re entitled to information about all the treatment options and the risks and benefits, clear explanations and enough details to give truly informed consent.

Australian patients have the right to access their dental records under Australian privacy laws. Clinics must keep accurate information about the patient’s care and provide it when asked.

Australia also has clear consumer protections around dental over-servicing. If treatment recommendations seem unnecessary, unsafe, or financially excessive, the Dental Board and the Australian Health Practitioner Regulation Agency can investigate.

Knowing these safeguards exist can make it easier to compare advice and feel confident you’re making the best decision for your mouth and your wallet.

Chanae Ihimaera, Senior Lecturer/Kaiwhakaako Oral Health, Auckland University of Technology

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Read More........→March 17, 2026